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More than half the patients had an improvement in at least three symptoms. Beverly Hills,CA90211 Hypogonadism returned, but was successfully treated with weekly injections of human chorionic gonadotropin for three months. DESIGN: Case report. BJU Int. Clomid. Tons of excellent references. Austin men's clinic austin urology institute Best urologist in austin Bladder cancer symptoms Central tx urology dr. shaw austin iud vs vasectomy low t center Austin mens health Austin North austin urology testosterone replacement therapy near me urological cancer surgeon texas urologic health urologist austin tx Urologist in austin vasectomy austin vasectomy doctor vasectomy infection vasectomy reversal vasectomy texas. If you have any form of cancer or are at risk of cancer, don't use DHEA. CONCLUSION(S): Clomiphene citrate is used typically in helping to restore fertility in females. Update: Crosnoe, Lindsey E., et al. It is most commonly treated by testosterone supplementation therapy but in younger patients this can lead to testicular atrophy with subsequent exogenous testosterone dependency and may impair spermatogenesis. 3 - Then remove the clomid and go with testosterone ONLY for six weeks - run the same labs at the same laboratory. Gonadotropin response to GnRH-stimulation test was studied by serial standard sampling after 100 microg GnRH i.v. Estrogen will still exists during trt. Zhonghua Nei Ke Za Zhi. J Sex Med. If those receptors are blocked even on trt GnRh will still be reliesed and stimulate LH and FSH. The Journal of Clinical Endocrinology & Metabolism January 1, 2011 vol. I was see a Dr. who prescribed Me HCG and at first I had slight Increases in T. but that was very short lived and my T dropped from 280 to 177. MAIN OUTCOME MEASURES:The main outcome measures were change in serum testosterone with CC and TGRT therapy, and change in the androgen deficiency in aging male (ADAM) questionnaire scores with CC therapy. 2005 Sep;2(5):716-21. When I went for the follow up the Dr. wanted to increase the HCG dosage but I referenced this article and she happily started me on Clomid. Katz DJ1, Nabulsi O, Tal R, Mulhall JP. The takeaway message is that having low testosterone symptoms is not just about feeling crummy, having difficulty with erections, low libido, fatigue, mood changes, drops in energy in the afternoons, sleeping problems or difficulty maintaining muscle mass it can also have an impact on your cardiovascular and bone health.Any type of testosterone supplementation is lifelong. If testosterone is used alone, or in combination with synthetic anabolic steroids, the circulating levels of testosterone are normal or high. plays a role in sperm production, fuels libido, and contributes to normal erections. No alcohol/food interactions were found. Pingback: Has anyone lost their libido and never had it return? LH and FSH then travel to the testicle to induce testosterone(LH) and sperm production (FSH). Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you. Results taking Clomid and Letrozole together w/ PCOS and Anovulation (Clomid 100mg, Letrozole 7.5mg) nursettc member. This disruption could be initiated by an abnormal physical condition or external drug source, especially in the case of young men. There were no side effects reported by the patients. Boost testosterone levels.One possible cause for poor semen health and low sperm counts can be low testosterone, and Clomid may be able to resolve this in specific cases. INTERVENTION(S): Clomiphene citrate, 100-mg challenge for 5 days, followed by treatment at same dose for 2 months. 27 However, it also carries the most reported side effectsmood swings, headaches, and altered vision at high dosages. Its clogs receptors in hypothalamus which respond to estrogen and limit Gnrh if enough estrogen is binding. How can they determine how high clomid is raising test levels when you are injecting testosterone? LH stimulation also helps maintain testicular size. 3) Increases Muscle Mass. Clomiphene citrate, and its derivatives, may allow for restoration of gonadal function by restoring physiologic pituitary function in a subset of patients with hypogonadism. Methods: This randomized phase IIB study enrolled 124 men with a morning serum T level of <250 ng/dL on 2 occasions. Copyright (c) 2012-13 Jeffrey Dach MD All Rights Reserved. Hill S, Arutchelvam V, Quinton R. Department of Clinical Pharmacology & Therapeutics, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK. Levels typically decrease 1-2% each year beginning at the age of 40. PATIENT(S): A 29-year-old male who has run 50 to 90 miles per week since 15 years of age and who presented with a pelvic stress fracture, markedly decreased bone mineral density, and symptomatic hypogonadotropic hypogonadism. J Sex Med. Keep in mind that Clomid tends to raise estrogen. Retrospective data collection was performed via chart review. I dont see how you can recover HPTA during TRT or a cycle and use clomid. Burge MR, Lanzi RA, Skarda ST, Eaton RP. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Traditionally, men diagnosed with low testosterone were started on testosterone replacement therapy (TRT or ART). INTRODUCTION:The efficacy of oral clomiphene citrate (CC) in the treatment of male hypogonadism and male infertility (MI) with low serum testosterone and normal gonadotropin levels has been reported. Often, when abnormal and typically age-related symptoms appear, it startles young men into looking deeper into the issue with the help of a healthcare professional. Clomiphene, more commonly referred to by its brand name Clomid, is a medication that was approved by the FDA following successful clinical trials in 1967. 3) HCG 5000IU twice weekly. Patients who have been on TRT and have decided to have children but want to maintain some increase in testosterone levels. SETTING:University-affiliated andrology practice within family practice clinic. These medications can get your fertility back on track by increasing the amount of bioavailable testosterone and decrease the amount of estradiol (a form of estrogen). Clomid is a non-steroid oral medication. PATIENT(S):Ten patients referred for male infertility evaluation. Epub 2009 Mar 6. Testosterone is in the drug class androgens and anabolic steroids. However, this improvement was short lived and lasted only one week, after which he reported a recurrence of more severe low testosterone symptoms, worse than before. Most physicians are not willing to go out past a year or two. The test result does not show common signs of low Testosterone. Male Fertility Drugs. My clinic gave me clomid 25mg 3x a week to prevent my testies from shutting down along with 150mg of test-cyp. Therefore, many of these young men are turning to testosterone replacement therapy for help. The compound also exhibited an unanticipated favorable effect on fasting plasma glucose; this result has been accompanied by rapidly accumulating evidence from other researchers for a bidirectional relationship between low serum testosterone and obesity/metabolic syndrome (syndrome X) in men. Participants needed for HSDD drug study (Addyi), Looking for opinions on recent labs (Clomid). My doc started me on Test injections 1cc per week about 120 days ago. This can result in testicular atrophy, fertility issues, acne, gynecomastia (breast enlargement), polycythemia (increased risk of blood clots) and can shut off the bodys natural system for producing testosterone. Each patient is different and the response will vary depending on current testosterone level. Our results suggest that clomiphene citrate-associated pyospermia has a negative effect on male fertility. a faster and higher release of follicle stimulating hormone aud. (1), Estrogen Receptors in the Hypothalamus Control the Whole Thing. Clomid is used to treat the following conditions: Testosterone is used to treat the following conditions. Gill GV.Endocrine Unit, Walton Hospital, Liverpool, UK. What is post-nut clarity and post-nut syndrome? In our patient, the hypothalamic Estrogen receptors were set to shut off at a relatively low estrogen level. All mean testosterone and gonadotropin measurements significantly increased during treatment. 60 capsules, each dosing 25 mg of clomiphene, costs $69.95 from Swiss Chems. Which test ester is best for not getting high rbc and henorit? TRT offers many benefits, including improved bone density and muscle mass, elevated mood, less body fat and enhanced libido. We offer both in-clinic and remote telemedicine consultations worldwide. I just asked my Endocrinologist and he would not prescribe it for me, Pingback: Testosterone Low Ki | testerone supplement, Pingback: Symptoms Of Low Testosterone In Males Over 50 | testosterone injections, Pingback: Something Your Doctor Forgot to Tell You About Testosterone Therapy, Pingback: Bioidentical Testosterone Reviews | how to increase testosterone. Because of preferential conversion of testosterone to estrogen in some men, elevated estrogen levels may require the addition of an aromatase inhibitor such as anastrazole (also called Arimidex). While testosterone replacement is the most common treatment, it can paradoxically lead to infertility, and may be a less physiologic therapy for patients with secondary hypogonadism due to pituitary dysfunction. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. West J Med. Clomid cannot and will not increase LH or increase testicular size while on TRT. This then triggers the production of LH (luteinizing hormone) and FSH (follicle stimulating hormone). Little Pink Pill AKA Female Viagra. The negative feedback initiated by having testosterone present will override any stimulation that clomid can provide. Even today, it is commonly used as a first-line treatment to help women experiencing infertility . Tan RS, Vasudevan D. Department of Family and Community Medicine, University of Texas Health Sciences Center, Houston, Texas 77030, USA. Upper left image : cropped portions of an anonymous body builder, courtesy of wikimedia commons. Taking DHEA to increase testosterone production might offer the following benefits, although data is limited: 2. Patients in all 3 treatment types reported similar levels of satisfaction with symptoms, with similar . The key difference between Clomid and TRT for low T is how the two medications raise testosterone levels. Eur J Appl Physiol. Mean femoral neck and lumbar spine BD scores improved significantly. Materials and Methods. 19) www.ncbi.nlm.nih.gov/pubmed/6435491 Testosterone Replacement Therapy ( TRT) is a popular and effective treatment for balancing hormones and boosting testosterone in the body. If that hurts people's feelings than estrogen blockers are an option. 1998 Jan;74(867):45-6. Clomid For Men With Low Testosterone Diagram is courtesy of Dr Rochira , Eur J Endocrinol. Decreased responses also occurred in men with diabetes, hypertension, coronary artery disease, and multiple medication use. Pingback: Clomid For Low Testosterone Reviews | testosterone bodybuilding, Pingback: Low Testosterone And Steroids | testosterone booster side effects, Pingback: Symptoms Of Low Testosterone In Men |. Originally it was used to increase ovulation and improve fertility in women. 1995 February; 162(2): 158160. The patient wished to retain fertility which contra-indicated the use of Testosterone preparations. So, with Clomid on board, the estrogen message to stop stop stop production of LH is silenced and the pituitary makes more LH, increasing the go go go to produce testosterone in the testes. 1) http://eje-online.org/content/155/4/513.long The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network. 2012 Aug;110(4):573-8. doi: 10.1111/j.1464-410X.2011.10702.x. Meaning that, in most cases, in order for low levels of testosterone to be increased, it is dependent on a medication taken consistently and throughout ones life. INTERVENTION(S): Clomiphene citrate (CC) at doses up to 50 mg two times per day over a 5-month period. vomiting. For those with lower than normal age-matched levels of testosterone treatment directed at normalizing testosterone with clomiphene citrate is a viable alternative to giving androgen supplements. Testosterone (free and total), sex hormone binding globulin, oestradiol, luteinizing hormone and follicle stimulating hormone were measured at baseline and during treatment on all patients. a healthcare professional, nor is it intended to provide specific medical advice and should not be used for the diagnosis or treatment of medical conditions. Clomid PCT Protocol. If a man is taking any form of supplemental testosterone (TRT), then his pituitary will go through a process called negative feedback resulting in the shutting down of LH. Now I am not denying that clomid has no affect on LH in the presence of exogenous testosterone, but I don't understand how clomid can raise endogenous levels to 900 or more, and the HPTA is still not shut down. He admitted to anabolic steroid abuse in the past, and now sought medical intervention to restore his testosterone to normal.. TRT may help to improve your health and quality of life. Rest assured, long-term use of clomid in males is safe. We describe two case histories that highlight some of the endocrine effects of doping with androgenic anabolic steroids. 2010 Jan;7(1 Pt 1):269-76. Doctors will also factor in other symptoms, which include: fatigue, low sexual desire, worsening sexual function, erection problems, weight gain, and. This stimulates the production of GnRH, gonadotropins. Clomiphene use in males is off label use, however. Its been used for decades in Europe but is there any safety data to substantiate that ?? Glenn R. Cunningham and Shivani M. Toma Baylor College of Medicine and St. Lukes Episcopal Hospital, Houston, Texas 77030 2009. I'd love a good explanation on this as well so I'll await other's replies. Anastrozole is actually FDA-approved for the treatment of breast cancer in women after surgery. Answer (1 of 5): Yes I would use hCG on trt, especially if fertility, testicular function, testicular size etc is important to you. Clomid for Men with Low Testosterone Part One. RESULT(S): Barely detectable levels of LH and FSH associated with hypogonadal levels of T were restored to the normal range with CC therapy. Some authors recommend taking Vitamin E to improve the success of Clomid. Interestingly, this generation of males is experiencing more cases of testosterone deficiency than any other. The largest testosterone increase was in Group . This is not a complete list of side effects and others may occur. Should you choose to take Clomid, your doctor will test your testosterone level a few weeks after initially starting the drug to make sure its at a healthy level. [The application of gonadotropin in treatment of male central hypogonadism]. Out of the ten men actively attempting conception, four pregnancies were achieved. Everyone else adheres to HCG for testicular atrophy. OBJECTIVE:In order to evaluate the effect of regulation induced by estradiol on the hypothalamic-pituitary-gonadal (HPG) axis, we studied the pulsatility of LH and FSH in two aromatase-deficient men (called subject 1 and subject 2), in which the production rate of estrogen (both local and circulating) is completely, or at least severely, impaired. Exogenous testosterone: a preventable cause of male infertility. Translational Andrology and Urology 2.2 (2013): 106-113. Int J Impot Res. Though its much more than simply to grow muscles. According to specialists, testosterone therapy can actually benefit the health of the patient in a variety of ways. What Happened in this Patient ? Patients who have a varicocele (a problem with the blood vessel around the testes) that can cause infertility. Epub 2006 Sep 27. 96 no. Welcome to ExcelMale.com, the leading and best-moderated mens health forum focused on increasing health, potency and productivity in men. Fertility is preserved. Use in males is "off-label". How is that endogenous 900 level from clomid different from the exogenous 900 level? Additionally, if a man using testosterone replacement therapy discontinued their medication, their levels of testosterone would immediately drop and their body would have to restart making its own testosterone. Thus, it lowers the level of circulating estradiol quite effectively. In a study published in 2012, conducted by Veterans Affairs in Seattle, Washington, researchers found that in men with low testosterone levels, testosterone treatment was associated with decreased mortality compared with no testosterone treatment.5. Clomid is a SERM taken to stimulate the pituitary to create and release more LH when someone is suspected of having secondary hypogonadism, which is defined by a failure or deficiency in LH that results in low testosterone. Clomid will still help with testicle size. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Is Testosterone Replacement Therapy Right For You? 2005 Nov;44(11):836-9. 2010 Jan;7(1 Pt 1):269-76. Strengthening the immune function. Clomid does not work this way.Clomiphine for low T is a different approach that helps increase testosterone and fertility in men. Decreased fat mass and obesity prevention. Enclomiphene (Androxal), in development by Repros Therapeutics Inc, is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. RESULTS:Estrogen treatment led to a significant reduction in both LH-pulsated frequency (7.5 +/- 0.7 in phase 1, 4.5 +/- 0.7 in phase 2) and amplitudes (3.5 +/- 0.006 in phase 1, 1.9 +/- 0.4 in phase 2) of peaks, whereas FSH showed only a conspicuous reduction in serum levels and a trend towards the reduction of the amplitudes of its peaks without modification of the frequency of the pulses. Complete reversal of adult-onset isolated hypogonadotropic hypogonadism with clomiphene citrate. Telegram A cycle of Clomid usually consists of 5 pills which cost around 10 per pill. DHEA also might increase the risk of hormone-sensitive cancers, including prostate, breast and ovarian cancers. |Want to know five simple ways to improve your health now? Testicular function remained normal thereafter on no treatment. Conclusion: Clomiphene for men with low testosterone is a viable option for younger males who wish to maintain fertility. Very simply, the pituitary gland in the brain is the director of testicular function. Hypogonadism Symptoms. There are many myths about low testosterone. morning erections). Many men find that using clomid for testosterone replacement therapy is just as effective as traditional TRT.Clomid has been around for quite some time. Austin Half Marathon 2023: Dr. Shaw and Alex Put Their Best Feet Forward, Wimberley Man Donates Kidney to Stranger with the Help of Dr. Shaw, Sexual Health (ED, Hormones, & Fertility), 12319 N. Mopac Expressway Suite 200, Austin, TX 78758, 940 W. University Ave, Georgetown, TX 78626, 27600 Ranch Road 12, Bldg 1, Dripping Springs, TX 78620, Decreased spontaneous erections (e.g. Male fertility pills can change a man's hormones (the endocrine system) in many ways. The result in men is a modest improvement in testosterone levels while preserving sperm production. The technical storage or access that is used exclusively for statistical purposes. Three of the four men with adult-onset idiopathic HH responded to CC alone with increases in testosterone, FSH, and LH. Testosterone is a male sex hormone. NYU Langone Medical Center Department of Urology, New York, New York 10016, USA. Clomid is used to treat the following conditions: Female Infertility; Lactation Suppression; Oligospermia; Ovulation Induction; testosterone. Great Article Prescribing is increasing in US but we really need a long term trial. RESULTS: Spontaneous nonbacterial pyospermia developed in CC-treated men [14.3%] at rate nearly twice that observed in controls [7.4%]. Clomid will work as well. Testosterone, Serum 51 ng/dL ***Treatment as follows: Provera 10mg x10 days (Period started 3rd day after completing Provera) Similar to females, males have an . Clomid is a synthetic estrogen, however. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The main outcome measures were predictors of response and long-term results with long-term CC therapy in hypogonadal patients. I take it during trt on and off. Patients who just do not want to deal with injection or pellet therapy and are willing to accept a lower T level. In some . The analysis of the pulsatility of LH and FSH was performed by sampling every 10 min for 8 h in the two phases. Four had Kallmanns syndrome, four idiopathic HH, and two panhypopituitarism. bolus in phases 1 and 2. breakthrough bleeding or spotting. Just like testosterone replacement therapy, Clomid must be prescribed and monitored by your doctor. It also focuses on lifestyle activities like exercise and nutrition for raising testosterone levels naturally or anything else related to testosterone the substance. The result in men is a modest improvement in testosterone levels while preserving sperm production. So, all at . Use Clomid together with testosterone? 6) www.ncbi.nlm.nih.gov/pubmed/19204885 I did have an increase in estrogen so we are now working on that. To learn more about low testosterone diagnosis and treatment options, make an appointment at Austin Urology Institute at 512.694.888 with a provider to discuss symptoms and explore options. Also note that concerning an answer which appears as an electronically posted question, I am NOT creating a physician patient relationship. Dr. Sean Breen explains the best method for testing hormone levels in both men and women. This therapy represents an alternative to testosterone therapy by stimulating the endogenous androgen production pathway. These can be combined together and used for a 4 week post cycle therapy cycle at dosages from 20mg to 50mg daily for each drug, depending on the level of suppression you've experienced or how powerful the SARMs were that you used. Reel back your attitude, please. Eur J Endocrinol. For those with lower than normal age-matched levels of testosterone treatment directed at normalizing testosterone with clomiphene citrate is a viable alternative to giving androgen supplements. Testosterone Replacement Therapy (TRT) is the replacement of the naturally declining Testosterone hormone in men. We performed a comprehensive literature search using PubMed through April 2020, using keywords such as clomid, CC, hypogonadism, infertility, symptoms, and testosterone.The list of publications was reviewed independently by two authors (B.J.H. Big Tex - I began TRT just about a year ago and my doc (very knowledgable and experienced, has written books on HRT) also prescribed Test Cyp together with 51 mg of Clomid M-W-F, Clomid being for testicular atrophy. 4) Combination therapy Clomiphene Citrate and HCG 5000IU. This treatment can be associated with skin irritation, gynecomastia, nipple tenderness, testicular atrophy, and decline in sperm counts. pain, redness, and swelling at the injection site. These and other questions answered by IMH doctors, IMH doctor discuss how Anabolic Steroids combined with medical supervision can benefit patients. Both testosterone and gonadotropins decreased during phase 2, whereas estradiol reached the normal range in both subjects. 5) Improves Mood and Libido. For a better experience, please enable JavaScript in your browser before proceeding. This therapy represents an alternative to testosterone therapy . 2013 Sep;1(5):749-57. doi: 10.1111/j.2047-2927.2013.00107.x. No, not Clomid. No adverse events were reported. 1 - Test TT, FT, LH and FSH after 6 weeks of testosterone ONLY. In this study we investigated the efficacy of clomiphene citrate in the treatment of hypogonadism with the objectives of raising endogenous serum testosterone (T) and improving the testosterone/estrogen (T/E) ratio. Serum estrogen was quite high at 72 pg/ml. Do you have a decrease in libido (sex drive)? Additionally, if one chooses to discontinue Clomid therapy they arent dropped off. The body is still producing its own testosterone and will slowly return to baseline lows over time. Objective To evaluate the effectiveness of clomiphene citrate (CC) in increasing endogenous T levels in obese men with low serum T and with IGT or T2DM treated . Source Male Sexual and Reproductive Medicine Programme, Urology Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, USA. . The cohort included all men with HG presenting to our clinic between 2002 and 2006 who, after an informed discussion, elected to have CC therapy. In men, Clomid works by stimulating the bodys own production of testosterone, effectively helping signal the testes to produce testosterone and thereby increase testosterone levels (assuming the cause of the initial problem is not in the testes ability to make testosterone). Clomiphene increases free testosterone levels in men with both secondary hypogonadism and erectile dysfunction: who does and does not benefit? PATIENTS AND METHODS: Forty-two nonpyospermic men with low serum testosterone levels treated with 25 mg CC/day were retrospectively compared to 27 untreated nonpyospermic men referred for infertility evaluation. 2003 Jun;15(3):156-65. Tamoxifen 10mg online FREE EXPRESS SHIPPING ON ALL DOMESTIC ORDERS OVER $300 passive exhalation through the mouth. I hope you are not a doctor, because of you are you need to spend another semester studying just Clomid. www.drdach.com RESULT(S):Clomiphene therapy resulted in complete normalization of pulsatile gonadotropin secretion, serum T level, and sexual function. Although identities will remain confidential as much as possible, as I can not control the media, I can not take responsibility for any breaches of confidentiality that may occur. Link to this article:http://wp.me/P3gFbV-1j. Clomid can be used for short periods with trt to bring testicles size up and luck start negative feed back for a bit. The drug then tricks the hypothalamus to produce more releasing hormone (GnHR), which in turn travels to the pituitary gland to increase LH and FSH production. LH and FSH in turn increase testosterone production, and sperm production, thus maintaining and enhancing fertility. Also, the lower the testosterone level, the longer it may take to see the benefits of Clomid versus traditional testosterone therapy. Fertil Steril. Case report: An 88-year-old gentleman who was admitted following recurrent episodes of confusion and falls was found to have a serum sodium level of 114 mmol/l, serum osmolality of 258 mosmol/l and urine . This increase is not as high as pellets or injections but it can make a big difference depending on how low you are. Male hypogonadism usually is treated with testosterone replacement to return testosterone levels to normal. HCG for reversing anabolic steroid abuse, 15) www.ncbi.nlm.nih.gov/pmc/articles/PMC2360778/?tool=pubmed www.ncbi.nlm.nih.gov/pubmed/9538490. When testosterone levels drop, a young male might experience low libido, erectile dysfunction, weight gain, poor concentration, depression, etc. www.truemedmd.com, Click Here for: Dr Dachs Online Store for Pure Encapsulations Supplements Six weeks later, the patient reported feeling like my old self with improved energy, libido and mood. For Part Two, Click Here. In men, Clomid works by stimulating the body's own production of testosterone, effectively helping signal the testes to produce testosterone and thereby increase . Why human growth hormone was ever banned from sports. Initial results were amazing. There is no reason for personal invective. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. After treatment, all patients felt stronger physically and 42/64 patients developed beard, pubes or armpit hair. The dosage range is 12.5mg 50mg per day. Semen parameters in this group also improved, and two of the three men achieved pregnancies with CC alone. Hypothalamic-pituitary-gonadal axis in two men with aromatase deficiency: evidence that circulating estrogens are required at the hypothalamic level for the integrity of gonadotropin negative feedback. Typically that type of fatigue coupled with low libido brings a young man into the doctors office for a check-up. Prevention of bone loss. This represents the first case report of the successful use of clomiphene to restore T levels and the pituitary-gonadal axis in a male patient.